athletes, is not an amino acid. It consists of ornithine bonded to two molecules of alpha ketoglutarate. Consumption of OKG has been common in Europe, especially in France, after surgery, burns, trauma and muscle wasting states; this is the reason why OKG is called “French tickler”.OKG can stimulate the hormone cascade by different mechanisms. Taking orally, it reduces the breakdown of the muscle tissues and loss of muscle amino acids (catabolism). OKG provides users with a potential release of growth hormone, an anti-catabolic effect, and an easily accessible source of glutamine and ornithine. It also stimulates the brain, boosts the immune system, and is an important ammonia scavenger.
Based on studies, a combination of glutamine, arginine, ornithine, and lysine has a synergistic effect on releasing GH. Most athletes who take OKG report that their performance increases, the duration of exercise lengthens, and exercise-induced fatigue takes longer to occur. Any athlete who does not take OKG is losing the advantages of a potent supplement.
Dosage and Side Effects:
No standard dosage has been determined, but most researchers recommend 6 to 12 grams per day. Because OKG raises the body`s glutamine levels and glutamine has a role in the recovery of glycogen`s resources, OKG can be used after events and workouts as a rebuilder of energy sources. I recommend that athletes take OKG one to two hours before exercise or at bedtime two hours after consuming a high protein food. 
As a GH releaser, OKG in doses of 10 grams or more is more effective than either ornithine or alpha ketoglutarate. OKG has an anti-aging effect too, because it can raise the levels of GH, strengthen the immune system, and prevent age-related muscle wasting.
OKG`s ability to increase protein synthesis, decrease protein break down, raise GH secretion, provide a source for glutamine and ornithine, elevate insulin levels, and provide anabolic-like effects have made it very popular with serious strength and endurance athletes. Some investigations claim that magnesium, vitamin C and vitamin B6 enhance the effectiveness of OKG.
